Taiwanese research finds relation between Tobacco and Lung Cancer

 

In some breaking news released by the Journal of Clinical Investigation, the Taiwanese research had finally identified the reason behind why tobacco causes lung cancer and other smoking-related damages to the human body as well.

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Moreover, the news was made cover story of the February release of the world’s leading biomedical journal.

According to the study, it clearly shows the mechanism of how tobacco-specific carcinogen causes lung cancer. It also reveals the important ingredient of tobacco carcinogen, nicotine-derived nitrosamine ketone (NNK), would induce the accumulation of a protein, DNA methyltranferase 1 (DNMT1), which reduces the tumor suppressor genes and thus it leads to lung cancer.

Meanwhile, it also reveals that the accumulation of DNMT1 in lung cancer patients who smoked regularly has very poor recovery chances.

Further, the report also says that if lung cancer patients leave smoking, after two or four weeks, the level of DNMT1 would start falling and it would result increase in the life span of the patient. Lung cancer patient who quit smoking can live eight or ten months more than who do not quit smoking.

Meanwhile, doctors can locate lung cancer samples and test for the stage of the DNMT1. Patients with low level of DNMT1 can avoid going through chemotherapy and radiotherapy as well.

The research was jointly conducted by researchers from National Cheng Kung University, National Taiwan Normal University, National Health Research Institute, National Yang-Ming University, China Medical University Hospital and National Taiwan University.